10 Tips for Maintaining Your Cleanroom Through Proactive Contamination Monitoring

Tip 1: Take Care of Your Equipment, Protect Your Data

Reliable decisions start with instruments you can trust. When monitoring equipment is neglected or calibrated late, the integrity of the data—and your cleanroom—begins to weaken. A single equipment failure can disrupt operations, undermine compliance, and leave your environment vulnerable. Protect your monitoring program by keeping every instrument properly maintained and calibrated, so you can rely on every data point to defend your processes.

Action: Check your calibration dates and, if necessary, order your routine calibration now for your PMS instrument. Order your calibration here

Tip 2: “Maintain” and “Calibrate” Your Carrier

Instruments need calibration — and so do the people who use them. Operators remain the largest source of potential contamination in any cleanroom, so rigorous training and regular requalification are essential safeguards.

Each team member must be fully trained in aseptic technique and requalified at least annually, or sooner if deviations occur. Making sure the operator knows exactly how to position and operate the sampler is critical to maintaining control.

Observe how personnel move, interact with equipment, and follow each step of the dressing process — even small errors in routine can pose significant risks.

Sharing trends and monitoring results with the entire team will build awareness, strengthen accountability, and reinforce pride in maintaining a controlled environment. When operators see how their actions directly affect monitoring results, they better understand their role in contamination control – and naturally sharpen their habits.